Summary statistics from genome-wide assocation analysis of LDL subfractions and their response to statin treatment

December 6, 2016

This webpage contains summary data accompanying the following publication:

Shim H, Chasman D I, Smith J D, Mora S, Ridker P M, Nickerson D A, Krauss R M and Stephens M (2015). A Multivariate genome-wide association analysis of 10 LDL subfractions, and their response to statin treatment, in 1868 Caucasians. PLoS ONE 10(4): e0120758.

Code implementing the data processing steps can be found here.

All data contained here are licensed under a Creative Commons Attribution 4.0 International license (CC-BY-4.0). To use these data for research, please cite the above paper published in PLoS ONE.


  1. README.txt: description of the data files.
  2. phenotypes.tar.gz: normalized averages and differences of LDL subfractions.
  3. genotypes.tar.gz: genotype data for selected SNPs.
  4. summary_stats_avg.tar.gz: summary statistics from genome-wide association analysis of averaged phenotype values. Genotypes are given in the BIMBAM genotype file format: *.geno files store genotype estimates, and *.meangeno files contain posterior mean genotype estimates. See Sections 3.3 and 3.4 of the BIMBAM software manual for more details.
  5. summary_stats_diff.tar.gz: summary statistics from genome-wide association analysis of differential phenotype values.